Picornavirus infection leading to immunosuppression

Molecular events leading to picornavirus genome replication.

COVID-19 infection leading to lethal spondylodiscitis with spinal abscess

Background: Secondary complications after SARS-CoV-2 virus infection including cardiovascular and neurological pose additional morbidity and mortality. Till date there no single case report of spondylodiscitis with spinal abscess after CVOID-19 infection. Case Description: A 71- year-old man presented with tachypnea and cough since 24 hours. He was febrile and the CT-chest showed typical pictu...

The relationship of immunosuppression to cytomegalovirus infection.

It has been pointed out that immunosuppression with cytotoxic, nonsteroidal drugs is associated with the development of cytomeglovirus (CMV) infection after renal transplantation, and that without such immunosuppression infection may not occur (3). What is not known is whether immunosuppression alone, without other factors peculiar to the transplant recipient, can cause CMV infection. One appro...

Immunosuppression in Helminth Infection

1.1 Parasitism Parasitism is an antagonistic relationship between organisms of different species where the parasite benefits at the expense of the host. Helminths are long-living, multicellular parasites. There are two major phylla of helminths; Nematodes and Platyhelminthes. The nematodes contain the intestinal worms known as soil-transmitted helminths including hookworms, whipworms and the fi...

Immunosuppression Induced by HIV Infection

Immunosuppression due to HIV infection is a resultant of several factors including defective innate signaling pathways, increased viral replication and virus load, gradual loss of peripheral CD4+T cells and depletion of T lymphocytes at mucosal sites that collectively lead to progressive immune deficiency and AIDS development. T cells derived from HIV patients were anergic and failed to mount a...